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ChemicalBook--->CAS DataBase List--->28459-40-7

28459-40-7

28459-40-7 Structure

28459-40-7 Structure
IdentificationBack Directory
[Name]

10-formyldihydrofolate
[CAS]

28459-40-7
[Synonyms]

C20H21N7O7
10-ForMyl-7
Folic acid IMpurity F
Folinic Acid IMpurity F
10-formyldihydrofolic acid
Folinic Acid EP Impurity F
Levofolinate EP Impurity F
Impurity F of Calcium Levofolinate
10-Formyl-7,8-dihydro Folic Acid Disodium Salt
10-ForMyl-7,8-dihydro Folic Acid (>85%) DisodiuM Salt
L-Glutamic acid,N-[4-[[(2-amino-3,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-
[Molecular Formula]

C20H21N7O7
[MOL File]

28459-40-7.mol
[Molecular Weight]

471.43
Chemical PropertiesBack Directory
[density ]

1.67±0.1 g/cm3(Predicted)
[pka]

3.38±0.10(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS08
[Signal word ]

Danger
[Hazard statements ]

H317-H334
[Precautionary statements ]

P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P261-P285-P304+P341-P342+P311-P501
Hazard InformationBack Directory
[Uses]

10-Formyl-7,8-dihydrofolic acid is a novel folate found in methotrexate-treated cells. 10-Formyldihydrofolate (H2folate) has not been found as a component of intracellular folates in normal tissues but has been identified in the cytosol of methotrexate (MTX)-treated MCF-7 breast cancer cells and normal human myeloid precursor cells.
[Definition]

ChEBI:10-formyldihydrofolic acid is the 10-formyl derivative of dihydrofolic acid. It is a conjugate acid of a 10-formyldihydrofolate(2-).
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