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ChemicalBook--->CAS DataBase List--->284462-80-2

284462-80-2

284462-80-2 Structure

284462-80-2 Structure
IdentificationBack Directory
[Name]

4-(2-carbamoyl-pyridin-4-yloxy)aniline
[CAS]

284462-80-2
[Synonyms]

Sorafenib impurity INT-2-M
Sorafenib tosylate Impurity 8
4-(2-carbamoyl-pyridin-4-yloxy)aniline
4-(4-AMINOPHENOXY)PYRIDINE-2-CARBOXAMIDE
2-Pyridinecarboxamide, 4-(4-aminophenoxy)-
[Molecular Formula]

C12H11N3O2
[MDL Number]

MFCD08692048
[MOL File]

284462-80-2.mol
[Molecular Weight]

229.23
Chemical PropertiesBack Directory
[Boiling point ]

462.5±40.0 °C(Predicted)
[density ]

1.315±0.06 g/cm3(Predicted)
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

14.79±0.50(Predicted)
[color ]

Brown to Dark Brown
[Stability:]

Light Sensitive
Hazard InformationBack Directory
[Uses]

4-(4-Aminophenoxy)-2-pyridinecarboxamide is an intermediate in the synthesis of N-Desmethyl Sorafenib (D293290). N-Desmethyl Sorafenib is a metabolite of Sorafenib (S676850) and has anti-proliferative activity in human breast cancer cells.
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