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ChemicalBook--->CAS DataBase List--->277299-70-4

277299-70-4

277299-70-4 Structure

277299-70-4 Structure
IdentificationBack Directory
[Name]

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
[CAS]

277299-70-4
[Synonyms]

EltroMbopag II
ELTROMBOPAG INT
Eltrombopag Impurity 35
Eltrombopag Intermediate 1
Eltrombopag olamine Intermediate 4
1-(3,4-Dimethylphenyl)-3-methyl-5-pyrazolone
1-(3,4-diMethylphenyl)-3-Methyl-1H-pyrazol-5-ol
2-(3,4-dimethylphenyl)-5-methyl-1H-pyrazol-3-one
2-Oxo-2,4,5,6,7,7a-Hexahydrothieno [3,2-c] Pyridine
2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one
1H-pyrazol-3(2H)-one,2-(3,4-Dimethylphenyl)-5-methyl-
2-(3,4-Dimethyl-phenyl)-5-methyl-1,2-dihydro-pyrazol-3-one
2-(3,4-dimethylphenyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one
2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
3H-Pyrazol-3-one, 2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-
2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one ISO 9001:2015 REACH
[EINECS(EC#)]

1592732-453-0
[Molecular Formula]

C12H14N2O
[MDL Number]

MFCD09795980
[MOL File]

277299-70-4.mol
[Molecular Weight]

202.25
Chemical PropertiesBack Directory
[Melting point ]

121.0 to 125.0 °C
[Boiling point ]

338.5±52.0 °C(Predicted)
[density ]

1.121
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

0.79±0.40(Predicted)
[color ]

Pale Beige to Light Beige
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H335-H319-H315
[Precautionary statements ]

P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501
[HS Code ]

2933.19.9000
Hazard InformationBack Directory
[Uses]

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one, is an impurity of Eltrombopag (E508000), which is agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.
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