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9A1P9 is a multi-tail ionizable cationic phospholipid.1 It induces membrane destabilization and has been used for organ-selective mRNA delivery to the spleen and liver and CRISPR-Cas9 gene editing in mice. | [References]
1. Liu, S., Cheng, Q., Wei, T., et al. Membrane-destabilizing ionizable phospholipids for organ-selective mRNA delivery and CRISPR-Cas gene editing Nat. Mater. 20(5),701-710(2021). |
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