| Identification | Back Directory | [Name]
Carbonic acid, (1R,2E,6S,10E,11aS,13S,14aR)-1,6,7,8,9,11a,12,13,14,14a-decahydro-1-hydroxy-6-methyl-4-oxo-4H-cyclopent[f]oxacyclotridecin-13-yl 3-pyridinylmethyl ester | [CAS]
2756173-91-6 | [Synonyms]
Carbonic acid, (1R,2E,6S,10E,11aS,13S,14aR)-1,6,7,8,9,11a,12,13,14,14a-decahydro-1-hydroxy-6-methyl-4-oxo-4H-cyclopent[f]oxacyclotridecin-13-yl 3-pyridinylmethyl ester | [Molecular Formula]
C23H29NO6 | [MOL File]
2756173-91-6.mol | [Molecular Weight]
415.48 |
| Hazard Information | Back Directory | [Description]
CHNQD-01255 significantly suppressed tumor growth (TGI = 61.0%) at a dose of 45 mg/kg (p.o.) in the xenograft model. Notably, the improved safety profile of CHNQD-01255 (MTD > 750 mg/kg, p.o.) was confirmed to be superior to that of BFA (MTD < 506 mg/kg). Overall, CHNQD-01255 may serve as a safe and effective new anti-HCC prodrug. |
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