| Identification | Back Directory | [Name]
4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] | [CAS]
27470-51-5 | [Synonyms]
ae-17
alfide
flogos
solurol
Aflogan
Calibene
Suxibuzona
SUXIBUZONE
lidinedione
Suxibuzonum
Suxibuzone CRS
Acetanilide Impurity 1
4-Hydroxymethylbutazolidine hemisuccinate
butanedioicacid,mono((4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl
succinicacid,monoesterwith4-butyl-4-(hydroxymethyl)-1,2-diphenyl-3,5-pyrazo
4-butyl-4-hydroxymethyl-1,2-diphenyl-3,5-pyrazolidinedionehydrogensuccinate
4-butyl-4-(beta-carboxypropionyl-oxymethyl)-1,2-diphenyl-3,5-pyrazolidinedio
4-Butyl-4-(beta-carboxypropionyl-oxymethyl)-1,2-diphenyl-3,5-pyrazolidinedione
4-((4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-yl)methoxy)-4-oxobutanoic acid
3-((4-Butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methoxycarbonyl)propionsaeure
3-(1,2-Diphenyl-3,5-dioxo-4-butylpyrazolidine-4-ylmethoxycarbonyl)propionic acid
Butanedioic acid, 1-[(4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl] ester
Succinic acid hydrogen (1,2-diphenyl-3,5-dioxo-4-butylpyrazolidin-4-yl)methyl ester
Succinic acid hydrogen (4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl ester
Succinic acid hydrogen 1-[(4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl] ester
4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER]
3,5-Pyrazolidinedione, 4-butyl-4-(hydroxymethyl)-1,2-diphenyl-, hydrogen succinate (ester) | [EINECS(EC#)]
248-477-6 | [Molecular Formula]
C24H26N2O6 | [MDL Number]
MFCD00079562 | [MOL File]
27470-51-5.mol | [Molecular Weight]
438.47 |
| Chemical Properties | Back Directory | [Appearance]
White or almost white, crystalline powder. | [Melting point ]
126-127° | [Boiling point ]
550.33°C (rough estimate) | [density ]
1.2847 (rough estimate) | [refractive index ]
1.6300 (estimate) | [storage temp. ]
2-8°C | [solubility ]
Practically insoluble in water, freely soluble in acetone, soluble in ethanol (96 per cent), practically insoluble in cyclohexane. | [form ]
neat | [pka]
4.33±0.17(Predicted) | [color ]
White to Off-White | [CAS DataBase Reference]
27470-51-5 |
| Hazard Information | Back Directory | [Chemical Properties]
White or almost white, crystalline powder. | [Uses]
analgesic, antipyretic, antiinflammatory | [Definition]
ChEBI: A pyrazolidine that is phenylbutazone which is substituted by a 3-carboxypropanoylmethyl group at the 4-position. Suxibuzone is a prodrug for phenylbutazone and is commonly used as an anti-inflammatory drug in horses. | [Brand name]
Calibene;Danalon om;Danilon;Flamilon;Flofos. | [World Health Organization (WHO)]
Suxibuzone, a pyrazolone derivative with anti-inflammatory,
analgesic and antipyretic activity, was introduced in 1974 for the treatment of
rheumatic disorders. As it is structurally related to phenylbutazone, it is subjected
to rigorously restricted indications by some national regulatory authorities. See
WHO comment for phenylbutazone. | [Biochem/physiol Actions]
A prodrug of phenylbutazone. | [storage]
Store at -20°C |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
20/21/22 | [Safety Statements ]
36 | [WGK Germany ]
3
| [RTECS ]
WM9640000
| [Toxicity]
LD50 orally in mice: 5.683 micromol/kg (Esteve, 1973) |
|
| Company Name: |
Spectrum Chemical Manufacturing Corp.
|
| Tel: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
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