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ChemicalBook--->CAS DataBase List--->2647442-13-3

2647442-13-3

2647442-13-3 Structure

2647442-13-3 Structure
IdentificationBack Directory
[Name]

INDEX NAME NOT YET ASSIGNED
[CAS]

2647442-13-3
[Synonyms]

GS-621763
SARS-CoV,GS-621763,GS 621763,Inhibitor,SARS coronavirus,inhibit,GS621763
[Molecular Formula]

C24H31N5O7
[MOL File]

2647442-13-3.mol
[Molecular Weight]

501.54
Chemical PropertiesBack Directory
[density ]

1.37±0.1 g/cm3(Predicted)
[storage temp. ]

4°C, away from moisture and light
[solubility ]

DMSO: 2mg/mL, clear
[form ]

Solid
[pka]

4.11±0.30(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Biological Activity]

GS-621763 is an orally bioavailable analog of remdesivirwhich is efficiently converted in plasma to active metabolite GS-441524or in lungs to the bioactive triphosphate GS-443902. GS-621763 effectively reduces SARS-CoV-2 burden to near-undetectable levels in ferrets.
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