Identification | Back Directory | [Name]
2H-Benz[g]indole-2,5(3H)-dione, 3,3-diethyl-4-(phenylmethoxy)- | [CAS]
2642218-43-5 | [Synonyms]
2H-Benz[g]indole-2,5(3H)-dione, 3,3-diethyl-4-(phenylmethoxy)- | [Molecular Formula]
C23H21NO3 | [MOL File]
2642218-43-5.mol | [Molecular Weight]
359.42 |
Chemical Properties | Back Directory | [Boiling point ]
532.4±60.0 °C(Predicted) | [density ]
1.20±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
-2.28±0.40(Predicted) | [color ]
Orange to red |
Hazard Information | Back Directory | [Uses]
RIG012 is a potent RIG-I inhibitor with an IC50 of 0.71 μM using the NADH-coupled ATPase assay. RIG012 inhibits IFN-β and ISG hRsad2 expression[1]. | [References]
[1] David C Rawling, et al. Small-Molecule Antagonists of the RIG-I Innate Immune Receptor. ACS Chem Biol. 2020 Feb 21;15(2):311-317. DOI:10.1021/acschembio.9b00810 |
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