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ChemicalBook--->CAS DataBase List--->2642218-43-5

2642218-43-5

2642218-43-5 Structure

2642218-43-5 Structure
IdentificationBack Directory
[Name]

2H-Benz[g]indole-2,5(3H)-dione, 3,3-diethyl-4-(phenylmethoxy)-
[CAS]

2642218-43-5
[Synonyms]

2H-Benz[g]indole-2,5(3H)-dione, 3,3-diethyl-4-(phenylmethoxy)-
[Molecular Formula]

C23H21NO3
[MOL File]

2642218-43-5.mol
[Molecular Weight]

359.42
Chemical PropertiesBack Directory
[Boiling point ]

532.4±60.0 °C(Predicted)
[density ]

1.20±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

-2.28±0.40(Predicted)
[color ]

Orange to red
Hazard InformationBack Directory
[Uses]

RIG012 is a potent RIG-I inhibitor with an IC50 of 0.71 μM using the NADH-coupled ATPase assay. RIG012 inhibits IFN-β and ISG hRsad2 expression[1].
[References]

[1] David C Rawling, et al. Small-Molecule Antagonists of the RIG-I Innate Immune Receptor. ACS Chem Biol. 2020 Feb 21;15(2):311-317. DOI:10.1021/acschembio.9b00810
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