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ChemicalBook--->CAS DataBase List--->2621928-53-6

2621928-53-6

2621928-53-6 Structure

2621928-53-6 Structure
IdentificationBack Directory
[Name]

2-Naphthalenol, 5-chloro-4-[4-(3,8-diazabicyclo[3.2.1]oct-3-yl)-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]pyrido[4,3-d]pyrimidin-7-yl]-
[CAS]

2621928-53-6
[Synonyms]

KRAS G12D inhibitor 5
2-Naphthalenol, 5-chloro-4-[4-(3,8-diazabicyclo[3.2.1]oct-3-yl)-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]pyrido[4,3-d]pyrimidin-7-yl]-
[Molecular Formula]

C31H31ClF2N6O2
[MOL File]

2621928-53-6.mol
[Molecular Weight]

593.07
Chemical PropertiesBack Directory
[density ]

1.51±0.1 g/cm3(Predicted)
[pka]

7.92±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

KRAS G12D inhibitor 5 is a KRAS G12D inhibitor for the potential research of pancreatic cancer.
[References]

[1] Kargbo RB. Targeting KRAS G12D Mutant for the Potential Treatment of Pancreatic Cancer. ACS Med Chem Lett. 2021 Oct 19;12(11):1643-1645. DOI:10.1021/acsmedchemlett.1c00545
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