Identification | Back Directory | [Name]
6-Bromo-2-naphthyl α-D-galactopyranoside | [CAS]
25997-59-5 | [Synonyms]
BR-NAP-ALPHA-D-GAL 6-BROMO NAPHTHYL GALACTOPYRANOSIDE 6-Bromo-2-naphthyl alpha-D-galactoside 6-Bromo-2-naphthyl-α-D-galactopyranoside 6-BROMO-2-NAPHTHYL-A-D-GALACTOPYRANOSIDE 6-Bromo-2-Naphthyl-Alpha-D-Galactopyran- BROMO-2-NAPHTHYL-A-D-GALACTOPYRANOSIDE, 6- alpha-D-6-Bromo-2-naphthylgalactopyranoside 6-BROMO-2-NAPHTHYL-ALPHA-D-GALACTOPYRANOSIDE 2-(6-BROMONAPHTHYL)-ALPHA-D-GALACTOPYRANOSIDE (6-Bromo-2-naphthalenyl)α-D-galactopyranoside BROMO-2-NAPHTHYL-a-D-GALACTOPYRANOSIDE, 6-(RG) 6-Bromo-2-naphthyl α-D-galactopyranoside USP/EP/BP (2R,3R,4S,5R,6R)-2-(6-bromonaphthalen-2-yl)oxy-6-(hydroxymethyl)oxane-3,4,5-triol (2R,3R,4S,5R,6R)-2-[(6-bromo-2-naphthyl)oxy]-6-methylol-tetrahydropyran-3,4,5-triol | [EINECS(EC#)]
247-398-4 | [Molecular Formula]
C16H17BrO6 | [MDL Number]
MFCD00066434 | [MOL File]
25997-59-5.mol | [Molecular Weight]
385.21 |
Hazard Information | Back Directory | [Uses]
6-Bromo-2-naphthyl α-D-galactopyranoside can be acted as a useful reagent for determination of alpha-D-Galactosidase activity.
| [Definition]
ChEBI: An alpha-D-galactoside having a 6-bromo-2-naphthyl substituent at the anomeric position. | [Purification Methods]
It is prepared from penta-O-acetyl-D-galactoside, 6-bromo-2naphthol and ZnCl2. The resulting tetra-acetate (2g) is hydrolysed by dissolving in 0.3N KOH (100mL) and heating until the solution is clear, then filtering and cooling to give colourless crystals of the -isomer which are collected and recrystallised twice from hot MeOH. The high specific rotation is characteristic of the isomer. The tetraacetate has m 155-156o, [] D 20 +60o (c 1, CHCl3) [Dey & Pridham Biochem J 115 47 1969] [reported m 75-85o, [] D 24 +94o (c 1.3, dioxane), Monis et al. J Histochem Cytochem 11 653 1963]. [Beilstein 17 IV 2972.] |
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