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ChemicalBook--->CAS DataBase List--->257892-31-2

257892-31-2

257892-31-2 Structure

257892-31-2 Structure
IdentificationBack Directory
[Name]

N-DESMETHYL ROSIGLITAZONE
[CAS]

257892-31-2
[Synonyms]

SB 237216
N-DESMETHYL ROSIGLITAZONE
N-Desmethyl Rosiglitazone Solution, 100ppm
5-[[4-[2-(2-pyridinylamino]ethoxy]phenyl]methyl]-2,4-thiazolidinedione
2,4-Thiazolidinedione, 5-[[4-[2-(2-pyridinylamino)ethoxy]phenyl]methyl]-
N-Desmethyl RosiglitazoneQ: What is N-Desmethyl Rosiglitazone Q: What is the CAS Number of N-Desmethyl Rosiglitazone Q: What is the storage condition of N-Desmethyl Rosiglitazone Q: What are the applications of N-Desmethyl Rosiglitazone
[Molecular Formula]

C17H17N3O3S
[MDL Number]

MFCD08063704
[MOL File]

257892-31-2.mol
[Molecular Weight]

343.4
Chemical PropertiesBack Directory
[Melting point ]

177-179°C
[storage temp. ]

-20°C Freezer
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

Off-White to Pale Beige
Hazard InformationBack Directory
[Description]

N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone (Item Nos. 71740 | 71742 | 11884), a potent and selective PPARγ ligand present in formulations that have been used to treat type 2 diabetes. Rosiglitazone is metabolized by the cytochrome P450 (CYP) isoform CYP2C8 to form N-desmethyl rosiglitazone.
[Chemical Properties]

White Solid
[Uses]

A metabolite of Rosiglitazone
[Uses]

A metabolite of Rosiglitazone.
[Definition]

ChEBI: N-desmethylrosiglitazone is an aromatic ether.
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