| Identification | Back Directory | [Name]
1,2-Benzisoselenazol-3(2H)-one, 2-[3-(trifluoromethyl)phenyl]- | [CAS]
2570461-66-2 | [Synonyms]
SARS-CoV-2-IN-7
1,2-Benzisoselenazol-3(2H)-one, 2-[3-(trifluoromethyl)phenyl]- | [Molecular Formula]
C14H8F3NOSe | [MOL File]
2570461-66-2.mol | [Molecular Weight]
342.17 |
| Chemical Properties | Back Directory | [Boiling point ]
414.5±55.0 °C(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 250 mg/mL (730.63 mM; Need ultrasonic) | [form ]
Solid | [pka]
-1.78±0.20(Predicted) | [color ]
Light yellow to orange |
| Hazard Information | Back Directory | [Biological Activity]
SARS-CoV-2-IN-7 inhibits viral replication with a nanomolar IC50 value (844 nM) in SARS-CoV-2-infected Vero E6 cells. | [References]
[1]. Huff S, et al. Discovery and Mechanism of SARS-CoV-2 Main Protease Inhibitors. J Med Chem. 2021 Sep 27:acs.jmedchem.1c00566. |
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