| Identification | Back Directory | [Name]
1-((3R,4R)-1-(cyclooctylmethyl)-3-(hydroxymethyl)piperidin-4-yl)-3-ethyl-1,3-dihydro-2H-benzo[d]imidazol-2-one | [CAS]
256640-45-6 | [Synonyms]
J-113397 >=98% (HPLC)
1-[(3R,4R)-1-(cyclooctylmethyl)-3-(hydroxymethyl)piperidin-4-yl]-3-ethylbenzimidazol-2-one
2H-Benzimidazol-2-one, 1-[(3R,4R)-1-(cyclooctylmethyl)-3-(hydroxymethyl)-4-piperidinyl]-3-ethyl-1,3-dihydro-
1-((3R,4R)-1-(cyclooctylmethyl)-3-(hydroxymethyl)piperidin-4-yl)-3-ethyl-1,3-dihydro-2H-benzo[d]imidazol-2-one | [Molecular Formula]
C24H37N3O2 | [MDL Number]
MFCD04113003 | [MOL File]
256640-45-6.mol | [Molecular Weight]
399.57 |
| Chemical Properties | Back Directory | [Melting point ]
145-145.5 °C(Solv: ethyl acetate (141-78-6)) | [Boiling point ]
518.5±43.0 °C(Predicted) | [density ]
1.109±0.06 g/cm3(Predicted) | [storage temp. ]
room temp | [solubility ]
DMSO: 2mg/mL, clear | [form ]
Solid | [pka]
14.93±0.10(Predicted) | [color ]
White to off-white | [optical activity]
[α]/D +7 to +10°, c =1 in isopropanol |
| Hazard Information | Back Directory | [Biological Activity]
J-113397 is an antagonist of NOPthe nociceptin/orphanin FQ (N/OFQ) receptor. J-113397 exhibited an IC50 value of 2.3 nM in Chinese hamster ovary (CHO) cells expressing ORL1 receptor showed with 600-fold or less affinity for μ-δ- and K-opioid receptors. |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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