| Identification | Back Directory | [Name]
UK-371804 hydrochloride | [CAS]
256476-36-5 | [Synonyms]
UK-371804 HCl
UK-371804 hydrochloride
UK-371,804 HCl >=98% (HPLC) | [Molecular Formula]
C14H17Cl2N5O4S | [MDL Number]
MFCD31558512 | [MOL File]
256476-36-5.mol | [Molecular Weight]
422.28 |
| Chemical Properties | Back Directory | [Melting point ]
258 °C (decomp) | [storage temp. ]
-20°C | [solubility ]
DMSO: 42 mg/mL (99.46 mM);Ethanol: Insoluble | [form ]
powder | [color ]
white to beige | [Water Solubility ]
Water: Insoluble |
| Hazard Information | Back Directory | [Biochem/physiol Actions]
UK-371,804 is a reversible, substrate-competitive, highly potent (Ki = 10 nM) and selective urokinase-type plasminogen activator (uPA) Inhibitor with excellent selectivity over tPA, plasmin, Factor IXa and Xa. When applied topically, UK-371,80 effectively penetrates into excisional wounds of experimental pigs with no adverse effect on wound closure. UK-371,804 effectively blocks EGR-FMK from binding human uPA even in the presence of tissue proteins. |
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| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Twochem Co.Ltd.
|
| Tel: |
021-58111628 15800915896 |
| Website: |
cn.twochem.com |
|