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ChemicalBook--->CAS DataBase List--->2561483-27-8

2561483-27-8

2561483-27-8 Structure

2561483-27-8 Structure
IdentificationBack Directory
[Name]

3H-Diazirine-3-propanamide, 3-(3-butyn-1-yl)-N-[5-cyano-6-[4-[3-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]benzoyl]-1-piperazinyl]-3-pyridinyl]-
[CAS]

2561483-27-8
[Synonyms]

PARPYnD
3H-Diazirine-3-propanamide, 3-(3-butyn-1-yl)-N-[5-cyano-6-[4-[3-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]benzoyl]-1-piperazinyl]-3-pyridinyl]-
[Molecular Formula]

C34H31N9O3
[MOL File]

2561483-27-8.mol
[Molecular Weight]

613.67
Chemical PropertiesBack Directory
[solubility ]

DMSO:61.37(Max Conc. mg/mL);100.0(Max Conc. mM)
Hazard InformationBack Directory
[Description]

PARPYnD is a potent photoaffinity probe for poly(ADP-ribose) polymerase (PARP) (IC50 values for PARP2, PARP1 and PARP6 are 6, 38 and 230 nM, respectively). PARPYnD labels PARP1 and PARP2 in the cell when an N3 functionalized fluorescent probe is attached and can inhibit isolated PARP6.
[storage]

Store at -20°C
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