| Identification | Back Directory | [Name]
1,6,7-Trihydroxyxanthone | [CAS]
25577-04-2 | [Synonyms]
7-Trihydroxyxanthone
1,6,7-Trihydroxyxanthone
1,6,7-trihydroxyxanthen-9-one
1,6,7-Trihydroxy-9H-xanthen-9-one
9H-Xanthen-9-one, 1,6,7-trihydroxy- | [Molecular Formula]
C13H8O5 | [MDL Number]
MFCD19441065 | [MOL File]
25577-04-2.mol | [Molecular Weight]
244.2 |
| Hazard Information | Back Directory | [Uses]
1,6,7-Trihydroxyxanthone is a potent anticancer agent. 1,6,7-Trihydroxyxanthone inhibits cell proliferation and induces cell Apoptosis. 1,6,7-Trihydroxyxanthone decreases Bmi-1 expressio and increases the protein levels expression of P14, P16[1]. | [References]
[1] Fu WM, et al. MiR-218-targeting-Bmi-1 mediates the suppressive effect of 1,6,7-trihydroxyxanthone on liver cancer cells. Apoptosis. 2015 Jan;20(1):75-82. DOI:10.1007/s10495-014-1047-3 |
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