| Identification | Back Directory | [Name]
cannabigerolic acid | [CAS]
25555-57-1 | [Synonyms]
CBGA
cannabigerolicaci
cannabigerolic acid
(E)-Cannabigerolic Acid
Cannabigerolic Acid (CRM)
Cannabigerolic acid solution
3-[(E)-3,7-Dimethyl-2,6-octadienyl]-2,4-dihydroxy-6-pentylbenzoic acid
2,4-Dihydroxy-3-[(2E)-3,7-dimethyl-2,6-octadienyl]-6-pentylbenzoic acid
Benzoic acid, 3-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-2,4-dihydroxy-6-pentyl- | [Molecular Formula]
C22H32O4 | [MDL Number]
MFCD08064808 | [MOL File]
25555-57-1.mol | [Molecular Weight]
360.49 |
| Chemical Properties | Back Directory | [Boiling point ]
535.7±50.0 °C(Predicted) | [density ]
1.082±0.06 g/cm3(Predicted) | [Fp ]
9℃ | [storage temp. ]
-70°C | [form ]
A neat solid | [pka]
3.42±0.43(Predicted) |
| Hazard Information | Back Directory | [Chemical Properties]
white to slightly yellowish crystalline powder. | [Uses]
cannabigerolic acid (CBGA), a major biosynthetic precursor molecule in cannabis,exhibits divergent effects on seizures in mouse models of epilepsy. CBGA is generated from geranyl pyrophosphate and olivetolic acid by Cannabis sativaprenyltransferase (CsPT4). | [Definition]
ChEBI: A dihydroxybenzoic acid that is olivetolic acid in which the hydrogen at position 3 is substituted by a geranyl group. A biosynthetic precursor to Delta9-tetrahydrocannabinol, the principal psychoactive constituent of th
cannabis plant. | [General Description]
A non-psychoactive cannabinoid, cannabigerolic acid (CBGA), is the precursor to THCA, CBDA, and CBCA cannabinoids in Cannabis. Cannabigerolic acid reportedly has efficacy in treatment of cancer and schizophrenia. This Certified Spiking Solution? is suitable for CBGA testing methods by HPLC, LC/MS, or GC/MS for applications in testing of Cannabis potency or impurity profiling, pharmaceutical research, and forensic analysis.
Cerilliant solution Certified Reference Materials (CRMs) of cannabinoids are supplied in a convenient, quantitative, US DEA-exempt solution format and with TK#s for Canadian customers. | [References]
[1] ISVETT JOSEFINA FLORES-SANCHEZ Robert V. PKS activities and biosynthesis of cannabinoids and flavonoids in Cannabis sativa L. plants.[J]. Plant and Cell Physiology, 2008, 49 12: 1767-1782. DOI:10.1093/pcp/pcn150.
[2] LYNDSEY L. ANDERSON. Cannabigerolic acid, a major biosynthetic precursor molecule in cannabis, exhibits divergent effects on seizures in mouse models of epilepsy[J]. British Journal of Pharmacology, 2021, 178 24: 4826-4841. DOI:10.1111/bph.15661.
[3] SUZUKI S, WAKANO C, MONTEILH-ZOLLER M K, et al. Cannabigerolic Acid (CBGA) inhibits the TRPM7 ion channel through its kinase domain[J]. Function, 2023, 32 16. DOI:10.1093/function/zqad069. |
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