| Identification | Back Directory | [Name]
citreoviridin | [CAS]
25425-12-1 | [Synonyms]
citreoviridin
CITREOVIRIDINE
Citreoviridin A
Citreoviridine A
(-)-citreoviridin
Citreoviridin, froM PenicilliuM citreoviride biourge
Citreoviridin, 97%, from Penicillium citreoviride biourge
6-[(1E,3E,5E,7E)-8-[(2R,3R,4R,5R)-3,4-dihydroxy-2,4,5-trimethyloxolan-2-yl]-7-methylocta-1,3,5,7-tetraenyl]-4-methoxy-5-methylpyran-2-one
D-Iditol, 2,5-anhydro-1,6-dideoxy-2-C-[(1E,3E,5E,7E)-8-(4-methoxy-5-methyl-2-oxo-2H-pyran-6-yl)-2-methyl-1,3,5,7-octatetraen-1-yl]-4-C-methyl-
4-Methoxy-5-methyl-6-[(1E,3E,5E,7E)-7-methyl-8-[(2S)-tetrahydro-3α,4β-dihydroxy-2,4,5β-trimethylfuran-2-yl]-1,3,5,7-octatetrenyl]-2H-pyran-2-one
4-Methoxy-5-methyl-6-[(1E,3E,5E,7E)-7-methyl-8-[(2S)-tetrahydro-3α,4β-dihydroxy-2,4,5β-trimethylfuran-2β-yl]-1,3,5,7-octatetrenyl]-2H-pyran-2-one
4-Methoxy-5-methyl-6-[(1E,3E,5E,7E)-7-methyl-8-[(2S)-tetrahydro-3α,4β-dihydroxy-2α,4,5β-trimethylfuran-2-yl]-1,3,5,7-octatetrenyl]-2H-pyran-2-one | [Molecular Formula]
C23H30O6 | [MDL Number]
MFCD00056086 | [MOL File]
25425-12-1.mol | [Molecular Weight]
402.48 |
| Chemical Properties | Back Directory | [Melting point ]
107-111℃ | [Boiling point ]
444.62°C (rough estimate) | [density ]
1.1271 (rough estimate) | [refractive index ]
1.4593 (estimate) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 10 mg/ml; Ethanol: 10 mg/ml | [form ]
Yellow to orange powder. | [pka]
13.67±0.70(Predicted) | [Stability:]
Light Sensitive |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow powder | [Uses]
Citreoviridin is a mycotoxin isolated from several Penicillium species that has been shown to inhibit the mitochondrial ATP synthetase system. It inhibits soluble ATPase (KD = 4.1 μM), ADP-stimulated respiration in isolated rat liver mitochondria (KD = 0.15 μM), and ATP-driven reduction of NAD+ by succinate (KD = 2 μM). Citreoviridin has been used to target ectopic ATPase activity in cancer cells in order to modulate the metabolic activity associated with tumorigenesis.[Cayman Chemical] | [Uses]
Citreoviridin is the dominant analogue of a family of tetraene mycotoxins with potent neurotoxic effects, produced by several species of Aspergillus and Penicillium. Citreoviridin inhibits mitochondrial ATPase and is a causative agent of cardiac beriberi. | [Definition]
ChEBI:Citreoviridin is a member of 2-pyranones. | [storage]
Store at -20°C |
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