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ChemicalBook--->CAS DataBase List--->253431-35-5

253431-35-5

253431-35-5 Structure

253431-35-5 Structure
IdentificationBack Directory
[Name]

28-epirapamycin
[CAS]

253431-35-5
[Synonyms]

28-epirapamycin
Rapamycin, (31S)-
28-Epirapamycin (>90%)
[Molecular Formula]

C51H79NO13
[MDL Number]

MFCD34470630
[MOL File]

253431-35-5.mol
[Molecular Weight]

914.17
Chemical PropertiesBack Directory
[Melting point ]

>120°C (dec.)
[storage temp. ]

-20°C Freezer
[solubility ]

Dichloromethane (Slightly), DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White to Light Yellow
Hazard InformationBack Directory
[Uses]

28-Epirapamycin is an epimer of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants.
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