| Identification | Back Directory | [Name]
(3S)-3-octanoyloxy-4-trimethylazaniumylbutanoate | [CAS]
25243-95-2 | [Synonyms]
L-Octanoylcarnitine
OCTANOYL-L-CARNITINE
O-octanoyl-L-carnitine
Octanoyl-L-carnitine >=97.0% (TLC)
(3S)-3-octanoyloxy-4-trimethylazaniumylbutanoate | [Molecular Formula]
C15H29NO4 | [MDL Number]
MFCD28580111 | [MOL File]
25243-95-2.mol | [Molecular Weight]
287.4 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [color ]
White to off-white | [optical activity]
[α]/D -17±2°, c = 1 in H2O | [BRN ]
5955761 |
| Hazard Information | Back Directory | [Uses]
Octanoyl-L-carnitine may be used as an analytical standard in the following:
- Separation and identification of underivatized octanoyl-L-carnitine in human plasma samples using high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC-MS/MS).
- Quantification of the analyte in biological samples of patients treated with continuous ambulatory peritoneal dialysis (CAPD) or automated peritoneal dialysis (APD) using high-performance liquid chromatography/tandem quadrupole mass spectrometry (HPLC-TQMS). The feasibility of adding L-carnitine to the peritoneal dialysis (PD) solution in APD-treated end-stage renal disease patients is investigated.
It may be used as a test material for investigating its rate of oxidation by mitochondria, isolated from the livers of fed, starved and glucagon treated virgin and lactating rats. | [Definition]
ChEBI: The L-enantiomer of an O-octanoylcarnitine. | [General Description]
Octanoyl-L-carnitine is a medium-chain endogenous ester of L-carnitine, obtained via acylcarnitine family transferase. | [Biochem/physiol Actions]
L-Octanoylcarnitine is the physiologically active form of octanoylcarnitine and is detected in medium-chain acyl-CoA dehydrogenase (MCAD) deficiency. MCAD is characterized by intolerance to prolonged fasting, recurrent episodes of hypoglycemic coma with medium-chain dicarboxylic aciduria, impaired ketogenesis, and low plasma and tissue carnitine levels. |
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