| Chemical Properties | Back Directory | [Boiling point ]
565.9±33.0 °C(Predicted) | [density ]
1.16±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Acetonitrile: 1mg/mL; Ethanol: 1mg/mL; Methanol: 1mg/mL | [form ]
A crystalline solid | [pka]
4.76±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
3β-OH-7-Oxocholenic acid is a bile acid.1 It is also a metabolite of 7β-hydroxy cholesterol in rats. Conjugated forms of 3β-OH-7-oxocholenic acid have been found in the urine of patients with Neimann-Pick disease type C.2,3 | [Definition]
ChEBI: 3beta-Hydroxy-7-oxochol-5-en-24-oic Acid is a bile acid. | [References]
1. Norii, T., Yamaga, N., and Yamasaki, K. Metabolism of 7β-hydroxycholesterol-4-14C in rat Steroids 15(3),303-326(1970).
2. Alvelius, G., Hjalmarson, O., Griffiths, W.J., et al. Identification of unusual 7-oxygenated bile acid sulfates in a patient with Niemann-Pick disease, type C J. Lipid Res. 42(10),1571-1577(2001).
3. Maekawa, M., Omura, K., Sekiguchi, S., et al. Identification of two sulfated cholesterol metabolites found in the urine of a patient with Niemann-Pick disease type C as novel candidate diagnostic markers Mass Spectrom. (Tokyo) 5(2),S0053(2016). |
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| Company Name: |
Merck KGaA
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(+86) 21 2033 8288 |
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http://www.sigmaaldrich.cn |
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