| Identification | Back Directory | [Name]
Isosparteine | [CAS]
24915-04-6 | [Synonyms]
Isosparteine
β-Isosparteine
b-Isosparteine
Isosparteine USP/EP/BP
(7S,7aβ,14aβ)-Dodecahydro-7α,14α-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine
(7S,7aβ,14S,14aβ)-Dodecahydro-7α,14α-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine
7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine,dodecahydro-, (7S,7aS,14S,14aS)- | [Molecular Formula]
C15H26N2 | [MDL Number]
MFCD00869353 | [MOL File]
24915-04-6.mol | [Molecular Weight]
234.38 |
| Chemical Properties | Back Directory | [alpha ]
D32 -15.3° (c = 2.3 in abs alc) | [Boiling point ]
bp0.2 100-110° | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder |
| Hazard Information | Back Directory | [Uses]
Sparteine (Lupinidine) is an alkaloid compound derived from leguminous plants and can act as a ganglionic blocker. Sparteine competitively inhibits the activity of the neuronal nicotinic acetylcholine receptor (nACh receptor)[1][2]. | [References]
[1] Voitenko S, et al. Effect of (+)-sparteine on nicotinic acetylcholine receptors in the neurons of rat superior cervical ganglion. Mol Pharmacol. 1991 Aug;40(2):180-5. PMID:1715014
[2] Cook D, et al. The alkaloid profiles of Lupinus sulphureus. J Agric Food Chem. 2009 Feb 25;57(4):1646-53. DOI:10.1021/jf803468q |
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