Identification | Back Directory | [Name]
1,2-DIOLEOYL-SN-GLYCEROL | [CAS]
24529-88-2 | [Synonyms]
18:1 DG ALN29882 Brn 1730457 1,2-SN-DIOLEIN sn-1,2-diolein (S)-1,2-DIOLEIN DG(18:1/18:1/0:0) 2-di-(s)-(-)-olei 1,2-sn-Dioleylglycerol L-Glycerol 1,2-dioleate L-Glycerol 2,3-dioleate sn-1,2-dioleoylglycerol Olein, 1,2-di-, (S)-(-)- glyceryl 1,2-sn-dioleate 1,2-DIOLEOYL-SN-GLYCEROL (S)-GLYCEROL 1,2-DIOLEATE (+)-L-Glycerol 1,2-dioleate 1-O,2-O-Dioleoyl-L-glycerol (-)-D-Glycerol 1,2-dioleate 1-O,2-O-Dioleoyl-D-glycerol 1,2-DIOLEOYL-SN-GLYCEROL, >=97% glycerol 1,2-di-(9Z-octadecenoate) 1 2-DIOLEOYL-SN-GLYCEROL AMPOULE* 1,2-BIS(O-9Z-OCTADECENOYL)-SN-GLYCEROL 1,2-DI[CIS-9-OCTADECENOYL]-SN-GLYCEROL 1,2-dioleoyl-sn-glycerol (C18:1,*(cis)-9) (Z)-(S)-3-hydroxypropane-1,2-diyl dioleate 1-(hydroxymethyl)-1,2-ethanediylester,(s)-9-octadecenoicacid(z) (9Z)-9-Octadecenoic acid 1,1′-[(1S)-1-(hydroxymethyl)-1,2-ethanediyl] ester 9-Octadecenoic acid (Z)-, 1-(hydroxymethyl)-1,2-ethanediyl ester, (S)- (9ci) 9-Octadecenoic acid(9Z)-, 1,1'-[(1S)-1-(hydroxymethyl)-1,2-ethanediyl] ester (S)-1,2-Diolein, (S)-Glycerol 1,2-dioleate, 1,2-Di(cis-9-octadecenoyl)-sn-glycerol | [Molecular Formula]
C39H72O5 | [MDL Number]
MFCD00148866 | [MOL File]
24529-88-2.mol | [Molecular Weight]
620.99 |
Chemical Properties | Back Directory | [Boiling point ]
670.8±35.0 °C(Predicted) | [density ]
0.9218 g/cm3 | [storage temp. ]
-20°C | [solubility ]
DMF: >20 mg/ml; DMSO: >7 mg/ml; Ethanol: >30 mg/ml; PBS pH 7.2: >250 μg/ml | [form ]
Liquid | [pka]
13.69±0.10(Predicted) | [color ]
Colorless to light yellow | [BRN ]
1730457 |
Hazard Information | Back Directory | [Description]
1,2-Dioleoyl-sn-glycerol is an analog of the protein kinase C-activating second messenger DAG. 1,2-Dioleoyl-sn-glycerol and 1,2-dioctanoyl-sn-glycerol are nearly equipotent in induction of the acrosome reaction in human sperm. | [Uses]
1,2-Dioleoyl-sn-glycerol is an analog of 1,3-Dioleoylglycerol (D4842100 which is used in the synthesis of amphiphilic gadolinium complexes as MRI contrast agents. | [Uses]
18:1 DG may be used:
- in the lipid-protein overlay screen assay with Arabidopsis Rho-like GTPases recombinant protein and Arabidopsis plasma membrane H+-ATPase
- in the preparation of the Golgi-like liposomes
- in giant unilamellar vesicles (GUVs) preparation
| [Definition]
ChEBI: A 1,2-diacyl-sn-glycerol in which the acyl groups at positions 1 and 2 are specified as oleoyl. | [General Description]
Diacylglycerol/diglyceride (DAG) is a glycerolipid, that is located at the plasma membrane. It is made up of two fatty acid chains that are covalently attached to a single glycerol molecule with the help of an ester linkage. | [Biochem/physiol Actions]
18:1 DG or 1,2-dioleoyl-sn-glycerol (DOG) fails to prevent the late fission events in the Golgi membrane. DOG is used in ferrihaem π–π tetramer aggregate preparation and β-haematin production. |
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