| Identification | Back Directory | [Name]
1H-Indole-3-propanamide, 2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]- | [CAS]
2446817-72-5 | [Synonyms]
APOL1-IN-1
1H-Indole-3-propanamide, 2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]- | [Molecular Formula]
C21H20FN3O3 | [MOL File]
2446817-72-5.mol | [Molecular Weight]
381.4 |
| Chemical Properties | Back Directory | [Boiling point ]
801.4±65.0 °C(Predicted) | [density ]
1.40±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 125 mg/mL (327.74 mM; Need ultrasonic) | [form ]
Solid | [pka]
13.03±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Biological Activity]
APOL1-IN-1 is a apolipoprotein L1 (APOL1) inhibitor extracted from patent WO2020131807A1 compound 87. APOL1-IN-1 can be used for the research of focal segmental glomerulosclerosis (FSGS) and non-diabetic kidney disease (NDKD)[1]. | [storage]
Store at -20°C | [References]
[1]. Brodney M, et, al. Inhibitors of apol1 and methods of using same. WO2020131807A1. |
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