| Identification | Back Directory | [Name]
4(3H)-Quinazolinone, 8-methyl-7-(1-propyn-1-yl)-2-[(2-pyrimidinylthio)methyl]- | [CAS]
2411890-36-1 | [Synonyms]
PARP11 inhibitor ITK7 (ITK7)
4(3H)-Quinazolinone, 8-methyl-7-(1-propyn-1-yl)-2-[(2-pyrimidinylthio)methyl]- | [Molecular Formula]
C17H14N4OS | [MOL File]
2411890-36-1.mol | [Molecular Weight]
322.38 |
| Chemical Properties | Back Directory | [Boiling point ]
528.4±60.0 °C(Predicted) | [density ]
1.29±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 2mg/mL, clear | [form ]
Solid | [pka]
-0.35±0.33(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Biological Activity]
ITK7 is a cell penetrantpotent and selective inhibitor of PARP11 mono-ADP-ribosylation (MARylation) activity. |
|
|