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ChemicalBook--->CAS DataBase List--->2408341-97-7

2408341-97-7

2408341-97-7 Structure

2408341-97-7 Structure
IdentificationBack Directory
[Name]

INDEX NAME NOT YET ASSIGNED
[CAS]

2408341-97-7
[Synonyms]

N-(1 -fluorocyclopropane-1 -carbonyl)-3-methyl-L-valyl-(4R)-N-((1 S)-2-carboxy-1 -[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyi}-4-hydroxy-L-prolinamide
[Molecular Formula]

C28H35FN4O6S
[MOL File]

2408341-97-7.mol
[Molecular Weight]

574.67
Chemical PropertiesBack Directory
[Boiling point ]

865.8±65.0 °C(Predicted)
[density ]

1.38±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

4.12±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

VH 101, acid is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development. VH 101, acid contains an E3 ligase ligand plus an alkyl linker with terminal amine ready for conjugation to a target protein ligand[1].
[IC 50]

VHL
[storage]

Store at -20°C
[References]

[1] Jian Jin, et al. Protein tyrosine kinase 6 (ptk6) degradation / disruption compounds and methods of use. WO2020010204A1.2020-01-09.
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