Identification | Back Directory | [Name]
INDEX NAME NOT YET ASSIGNED | [CAS]
2408341-97-7 | [Synonyms]
N-(1 -fluorocyclopropane-1 -carbonyl)-3-methyl-L-valyl-(4R)-N-((1 S)-2-carboxy-1 -[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyi}-4-hydroxy-L-prolinamide | [Molecular Formula]
C28H35FN4O6S | [MOL File]
2408341-97-7.mol | [Molecular Weight]
574.67 |
Chemical Properties | Back Directory | [Boiling point ]
865.8±65.0 °C(Predicted) | [density ]
1.38±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
4.12±0.10(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
VH 101, acid is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development. VH 101, acid contains an E3 ligase ligand plus an alkyl linker with terminal amine ready for conjugation to a target protein ligand[1]. | [IC 50]
VHL | [storage]
Store at -20°C | [References]
[1] Jian Jin, et al. Protein tyrosine kinase 6 (ptk6) degradation / disruption compounds and methods of use. WO2020010204A1.2020-01-09. |
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R&D Systems, Inc
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18003437475 18003437475 |
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www.rndsystems.com |
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