| Identification | Back Directory | [Name]
2H-Indol-2-one, 1,3-dihydro-3-(4-hydroxyphenyl)-3-[4-(trifluoromethoxy)phenyl]-7-(trifluoromethyl)-, (3S)- | [CAS]
2407860-34-6 | [Synonyms]
(S)-ErSO
2H-Indol-2-one, 1,3-dihydro-3-(4-hydroxyphenyl)-3-[4-(trifluoromethoxy)phenyl]-7-(trifluoromethyl)-, (3S)- | [Molecular Formula]
C22H13F6NO3 | [MOL File]
2407860-34-6.mol | [Molecular Weight]
453.33 |
| Chemical Properties | Back Directory | [Boiling point ]
485.0±45.0 °C(Predicted) | [density ]
1.461±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, away from moisture and light | [solubility ]
DMSO : 190 mg/mL (419.12 mM; Need ultrasonic) | [form ]
Solid | [pka]
9?+-.0.30(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Biological Activity]
(S)-ErSO is the dextrorotatory enantiomer of ErSO. (S)-ErSO is inactive in MCF-7 cells (from patent WO2020009958A1, compound (s)-105)[1].
(-)-ErSO induces dose-dependent death of MCF-7 cells. (+)-l05 is inactive[1]. | [References]
[1]. David J. Shapiro, et al. Activators of the unfolded protein response. WO2020009958A1. |
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DC Chemicals
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