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ChemicalBook--->CAS DataBase List--->2389988-59-2

2389988-59-2

2389988-59-2 Structure

2389988-59-2 Structure
IdentificationBack Directory
[Name]

1-Amino-3'-deoxy-7,8-dihydro-8-oxoguanosine
[CAS]

2389988-59-2
[Synonyms]

1-Amino-3'-deoxy-7,8-dihydro-8-oxoguanosine
1-Amino-3’-deoxy-7,8-dihydro-8-oxoguanosine
[Molecular Formula]

C10H14N6O5
[MDL Number]

MFCD31707525
[MOL File]

2389988-59-2.mol
[Molecular Weight]

298.26
Chemical PropertiesBack Directory
[density ]

2.32±0.1 g/cm3(Predicted)
[pka]

7.96±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

1-Amino-3’-deoxy-7,8-dihydro-8-oxoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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