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ChemicalBook--->CAS DataBase List--->2380228-45-3

2380228-45-3

2380228-45-3 Structure

2380228-45-3 Structure
IdentificationBack Directory
[Name]

Ethenesulfonamide, N-[4-(2-naphthalenylmethyl)phenyl]-
[CAS]

2380228-45-3
[Synonyms]

DC-TEADin02
Ethenesulfonamide, N-[4-(2-naphthalenylmethyl)phenyl]-
[Molecular Formula]

C19H17NO2S
[MOL File]

2380228-45-3.mol
[Molecular Weight]

323.41
Chemical PropertiesBack Directory
[Boiling point ]

501.7±53.0 °C(Predicted)
[density ]

1.268±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

8.23±0.50(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

DC-TEADin02 is a potent TEAD autopalmitoylation inhibitor. DC-TEADin02 has TEAD autopalmitoylation inhibitory with the IC50 value of 197 nM. DC-TEADin02 can be used for the research of development, regeneration and tissue homeostasis[1].
[References]

[1] Wenchao Lu, et al. Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors. Eur J Med Chem. 2019 Dec 15;184:111767. DOI:10.1016/j.ejmech.2019.111767
Spectrum DetailBack Directory
[Spectrum Detail]

Ethenesulfonamide, N-[4-(2-naphthalenylmethyl)phenyl]-(2380228-45-3)1HNMR
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