| Identification | Back Directory | [Name]
Benzoic acid, 3-[[[4-[(4-fluorophenyl)methoxy]-3-methylphenyl]methyl]amino]- | [CAS]
2376590-40-6 | [Synonyms]
CAY10767
Benzoic acid, 3-[[[4-[(4-fluorophenyl)methoxy]-3-methylphenyl]methyl]amino]- | [Molecular Formula]
C22H20FNO3 | [MDL Number]
MFCD34475757 | [MOL File]
2376590-40-6.mol | [Molecular Weight]
365.4 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 20mg/mL,DMF:PBS (pH 7.2) (1:2): 0.3mg/mL,DMSO: 5mg/mL,Ethanol: 12mg/mL | [form ]
A crystalline solid |
| Hazard Information | Back Directory | [Biological Activity]
CAY10767 is an agonist of peroxisome proliferator-activated receptor α (PPARα; EC50 = 37 nM in a reporter assay).1 It is greater than 2,700-fold selective for PPARα over PPARγ or PPARδ. | [storage]
Store at -20°C | [References]
1.Dou, X., Nath, D., Shin, H., et al.Evolution of a 4?benzyloxy-benzylamino chemotype to provide efficacious, potent, and isoform selective PPARα agonists as leads for retinal disordersJ. Med. Chem.63(6)2854-2876(2020)
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ChemeGen 中國
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18818260767 |
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https://www.chemegen.com |
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