Chemical Properties | Back Directory | [Boiling point ]
758.6±60.0 °C(Predicted) | [density ]
1.23±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
9.25±0.20(Predicted) | [color ]
Light yellow to yellow |
Hazard Information | Back Directory | [Biological Activity]
DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM[1]. | [storage]
Store at -20°C | [References]
[1]. Arai Y, et al. Discovery of novel PTHR1 antagonists: Design, synthesis, and structure activity relationships. Bioorg Med Chem Lett. 2019 Sep 15;29(18):2613-2616. |
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