Identification | Back Directory | [Name]
5-(5-((1S,2R)-2-isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione | [CAS]
2375815-63-5 | [Synonyms]
EX-A4254 CD73-IN-3 LY-3475070 5-[6-Methyl-5-[(1S,2R)-2-propan-2-ylcyclopropyl]pyridazin-3-yl]-1H-pyrimidine-2,4-dione 5-(5-((1S,2R)-2-isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione | [Molecular Formula]
C15H18N4O2 | [MDL Number]
MFCD33029253 | [MOL File]
2375815-63-5.mol | [Molecular Weight]
286.34 |
Chemical Properties | Back Directory | [density ]
1.245±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 100 mg/mL (349.25 mM; Need ultrasonic) | [form ]
Solid | [pka]
7.25±0.10(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
CD73-IN-3 is a potent CD73 inhibitor (IC50=7.3 nM in Calu6 human cell assay). CD73-IN-3, example 2 extracted from patent WO2019168744 A1, has the potential for cancer research[1]. | [storage]
Store at -20°C | [References]
[1] Robert Dean Dally, et al. Cd73 inhibitors. Patent WO2019168744 A1. |
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DC Chemicals
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