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ChemicalBook--->CAS DataBase List--->2375815-63-5

2375815-63-5

2375815-63-5 Structure

2375815-63-5 Structure
IdentificationBack Directory
[Name]

5-(5-((1S,2R)-2-isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione
[CAS]

2375815-63-5
[Synonyms]

EX-A4254
CD73-IN-3
LY-3475070
5-[6-Methyl-5-[(1S,2R)-2-propan-2-ylcyclopropyl]pyridazin-3-yl]-1H-pyrimidine-2,4-dione
5-(5-((1S,2R)-2-isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione
[Molecular Formula]

C15H18N4O2
[MDL Number]

MFCD33029253
[MOL File]

2375815-63-5.mol
[Molecular Weight]

286.34
Chemical PropertiesBack Directory
[density ]

1.245±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 100 mg/mL (349.25 mM; Need ultrasonic)
[form ]

Solid
[pka]

7.25±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

CD73-IN-3 is a potent CD73 inhibitor (IC50=7.3 nM in Calu6 human cell assay). CD73-IN-3, example 2 extracted from patent WO2019168744 A1, has the potential for cancer research[1].
[storage]

Store at -20°C
[References]

[1] Robert Dean Dally, et al. Cd73 inhibitors. Patent WO2019168744 A1.
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