Identification | Back Directory | [Name]
N-Hydroxy-6-[[[3-methyl-4-[(2-methyl[1,1′-biphenyl]-3-yl)methoxy]phenyl]methyl]amino]hexanamide | [CAS]
2364448-93-9 | [Synonyms]
N-Hydroxy-6-[[[3-methyl-4-[(2-methyl[1,1′-biphenyl]-3-yl)methoxy]phenyl]methyl]amino]hexanamide | [Molecular Formula]
C28H34N2O3 | [MOL File]
2364448-93-9.mol | [Molecular Weight]
446.58 |
Hazard Information | Back Directory | [Uses]
SP-2-225 is a selective HDAC6 inhibitor. SP-2-225 enhance the production of cancer-associated antigens and macrophage antigen cross-presentation to T cells. SP-2-225 reduces the tumor volume in a syngeneic SM1 melanoma model[1]. | [References]
[1] Scott Grindrod, et al. Abstract PO023: Immune-mediated tumor growth inhibition by selective HDAC6 inhibitor SP-2-225. Cancer Immunol Res (2021) 9 (2_Supplement): PO023. |
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