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ChemicalBook--->CAS DataBase List--->2341796-77-6

2341796-77-6

2341796-77-6 Structure

2341796-77-6 Structure
IdentificationBack Directory
[Name]

VH 032-linker 8
[CAS]

2341796-77-6
[Synonyms]

VH 032-linker 8
(S,R,S)-AHPC-C6-amine
VH 032 amide-alkylC6-amine
(S,R,S)-AHPC-C6-NH2 hydrochloride
(S,R,S)-AHPC-C6-NH2 (dihydrochloride)
[Molecular Formula]

C29H44ClN5O4S
[MOL File]

2341796-77-6.mol
[Molecular Weight]

594.21
Chemical PropertiesBack Directory
[solubility ]

Soluble in DMSO
Hazard InformationBack Directory
[Uses]

(S,R,S)-AHPC-C6-NH2 dihydrochloride (VH032-C6-NH2 dihydrochloride) is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the VH032 based VHL ligand and a linker used for?AKT?PROTAC degrader. (S,R,S)-AHPC-C6-NH2 dihydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1[1].
[IC 50]

VHL
[storage]

Store at -20°C
[References]

[1] Jian Jin, et al. Serine threonine kinase (akt) degradation / disruption compounds and methods of use. Patent WO2019173516A1.
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