| Identification | Back Directory | [Name]
4-Pyridinecarboxamide, 2-(cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-, hydrochloride (1:2) | [CAS]
2320953-89-5 | [Synonyms]
4-Pyridinecarboxamide, 2-(cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-, hydrochloride (1:2) | [Molecular Formula]
C22H29ClN4O2 | [MOL File]
2320953-89-5.mol | [Molecular Weight]
416.95 |
| Chemical Properties | Back Directory | [storage temp. ]
Desiccate at RT | [solubility ]
Soluble to 100 mM in water and to 100 mM in DMSO | [Water Solubility ]
water|45.34|100|DMSO|45.34|100| |
| Hazard Information | Back Directory | [Description]
Potent and selective PRMT5 inhibitor (IC50 = 4 nM). Selective for PRMT5 over a panel of other PRMTs and lysine methyltransferases. Inhibits proliferation of mantle cell lymphoma (MCL) in vitro. To request the negative control for GSK 591, please fill out the SGC 2096 request form on the SGC website. | [storage]
Desiccate at RT |
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