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ChemicalBook--->CAS DataBase List--->2318792-30-0

2318792-30-0

2318792-30-0 Structure

2318792-30-0 Structure
IdentificationBack Directory
[Name]

ERK5-IN-5
[CAS]

2318792-30-0
[Synonyms]

ERK5-IN-5
[Molecular Formula]

C19H16ClN3O
[MOL File]

2318792-30-0.mol
[Molecular Weight]

337.8
Chemical PropertiesBack Directory
[density ]

1.364±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

13.945±0.40(predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

ERK5-IN-5 (compound 4a) is an ERK5 kinase inhibitor with anticancer activity. ERK5-IN-5 exhibits good anti-proliferative activity with the IC50 value of 6.23 μg/mL for A549 cells[1].
[IC 50]

ERK5
[References]

[1] Qin Zhang, et al. Design, synthesis and SAR of novel 7-azaindole derivatives as potential Erk5 kinase inhibitor with anticancer activity. Bioorg Med Chem. 2023 Oct 14:95:117503. DOI:10.1016/j.bmc.2023.117503
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