| Identification | Back Directory | [Name]
HOOCCH2O-PEG4-CH2CH2COOtBu | [CAS]
2304558-22-1 | [Synonyms]
Acid-C1-PEG5-Boc
t-butyl ester-PEG5-CH2COOH
HOOCCH2O-PEG4-CH2CH2COOtBu | [Molecular Formula]
C17H32O9 | [MDL Number]
MFCD31811452 | [MOL File]
2304558-22-1.mol | [Molecular Weight]
380.43 |
| Chemical Properties | Back Directory | [Boiling point ]
483.4±40.0 °C(Predicted) | [density ]
1.121±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Water, DMSO, DMF | [form ]
Liquid | [pka]
3.39±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
t-butyl ester-PEG5-CH2COOH is a PEG linker containing a t-butyl protected carboxyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. |
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