| Identification | Back Directory | [Name]
1H-1,2,3-Triazole-4-carboxamide, 1-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethyl]-N-[4-[[4-[[[2-[methyl(methylsulfonyl)amino]-3-pyridinyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]phenyl]- | [CAS]
2271035-37-9 | [Synonyms]
1H-1,2,3-Triazole-4-carboxamide, 1-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethyl]-N-[4-[[4-[[[2-[methyl(methylsulfonyl)amino]-3-pyridinyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]phenyl]- | [Molecular Formula]
C41H42F3N13O9S | [MOL File]
2271035-37-9.mol | [Molecular Weight]
949.91 |
| Chemical Properties | Back Directory | [density ]
1.57±0.1 g/cm3(Predicted) | [solubility ]
Soluble to 100 mM in DMSO | [form ]
Solid | [pka]
10.60±0.70(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Description]
FC-11 is a potent FAK-targeting PROTAC. FC-11 showed a rapid and reversible FAK degradation with a picomolar of DC50 in various cell lines in vitro, which imply that FAK-PROTACs could be useful as expand tools for studying functions of FAK in biological system and as potential therapeutic agents. | [storage]
Store at -20°C |
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