| Identification | Back Directory | [Name]
Bacitracin F, 1-[N-[[2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl]carbonyl]-l-leucine]- | [CAS]
22601-59-8 | [Synonyms]
Solu-tracin 50
Bacitracin A (Technical Grade)
1-[N-[[2-(1-Amino-2-methylbuyl)-4,5-dihydro-4-thiazolyl]carbonyl]-L-leucine]bacitracin F
Bacitracin F, 1-[N-[[2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl]carbonyl]-l-leucine]-
N2-[N-[[2-(1-Amino-2-methylbutyl)-4,5-dihydrothiazol-4-yl]carbonyl]-L-Leu-D-Glu-L-Ile-]cyclo(L-Lys-D-Orn-L-Ile-D-Phe-L-His-D-Asp-L-Asn-)
L-Asparagine, N-[[(4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-4-thiazolyl]carbonyl]-L-leucyl-D-α-glutamyl-L-isoleucyl-L-lysyl-D-ornithyl-L-isoleucyl-D-phenylalanyl-L-histidyl-D-α-aspartyl-, (10→4)-lactam | [EINECS(EC#)]
245-115-9 | [Molecular Formula]
C66H103N17O16S | [MOL File]
22601-59-8.mol | [Molecular Weight]
1422.71 |
| Chemical Properties | Back Directory | [Melting point ]
>190°C (dec.) | [storage temp. ]
2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [Boiling point ]
1755.5±65.0 °C(Predicted) | [density ]
1.43±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
4.01±0.10(Predicted) | [color ]
White to Pale Yellow | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
Bacitracin A is a peptide antibiotic. | [Definition]
ChEBI: Bacitracin A is a homodetic cyclic peptide consisting of (4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carboxylic acid attached head-to-tail to L-leucyl,D-glutamyl, L-lysyl, D-ornityl, L-isoleucyl, D-phenylalanyl, L-histidyl. D-aspartyl and L-asparaginyl residues coupled in sequence and cyclised by condensation of the side-chain amino group of the L-lysyl residue with the C-terminal carboxylic acid group. It is the major component of bacitracin. It has a role as an antibacterial agent and an antimicrobial agent. It is a homodetic cyclic peptide and a polypeptide. |
|
|