Chemical Properties | Back Directory | [Boiling point ]
564.3±50.0 °C(Predicted) | [density ]
1.41±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 50 mg/mL (99.31 mM); Water: < 0.1 mg/mL (insoluble) | [form ]
Solid | [pka]
13.20±0.70(Predicted) | [color ]
Light yellow to yellow |
Hazard Information | Back Directory | [Uses]
NVP-BHG712 isomer, a regioisomer of NVP-BHG712, shows conserved non-bonded binding to EPHA2 and EPHB4[1]. | [Biological Activity]
NVP-BHG712 isomer, a positional isomer of NVP-BHG712, shows conserved non-bonded binding to EPHA2 and EPHB4. | [in vitro]
NVP-BHG712 isomer exhibits IC 50 values of 163 nM and 1660 nM for EPHA2 and EPHA4, respectively. p> | [target]
| [storage]
Store at -20°C | [References]
[1] Tr?ster A, et al. NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family. ChemMedChem. 2018 Aug 20;13(16):1629-1633. DOI:10.1002/cmdc.201800398 |
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DC Chemicals
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Biorbyt Ltd.
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www.biorbyt.com |
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