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ChemicalBook--->CAS DataBase List--->2239305-70-3

2239305-70-3

2239305-70-3 Structure

2239305-70-3 Structure
IdentificationBack Directory
[Name]

IACS-8968 (S-enantiomer)
[CAS]

2239305-70-3
[Synonyms]

IACS-8968 S-entiomer
IACS-8968 (S-enantiomer)
IDO/TDO Inhibitor (S-enantiomer)
1,3,8-Triazaspiro[4.5]decane-2,4-dione, 6,6-dimethyl-8-[7-(trifluoromethyl)imidazo[1,5-a]pyridin-5-yl]-, (5S)-
[Molecular Formula]

C17H18F3N5O2
[MOL File]

2239305-70-3.mol
[Molecular Weight]

381.35
Chemical PropertiesBack Directory
[density ]

1.55±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

9.95±0.40(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

IACS-8968 (S-enantiomer) is the S-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor, with pIC50s of 6.43 for IDO and <5 for TDO, respectively.
[References]

[1] ARYL SULFONOHYDRAZIDES. WO 2017189386 A1.
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