| Identification | Back Directory | [Name]
4-[4-(1H-Imidazol-1-yl)phenyl]-N-2-propyn-1-yl-2-pyrimidinamine | [CAS]
2234272-10-5 | [Synonyms]
4-[4-(1H-Imidazol-1-yl)phenyl]-N-2-propyn-1-yl-2-pyrimidinamine
2-Pyrimidinamine, 4-[4-(1H-imidazol-1-yl)phenyl]-N-2-propyn-1-yl- | [Molecular Formula]
C16H13N5 | [MDL Number]
MFCD32697259 | [MOL File]
2234272-10-5.mol | [Molecular Weight]
275.31 |
| Hazard Information | Back Directory | [Biological Activity]
AP-C5 is a potent and selective inhibitor of the guanosine 3′,5′-cyclicmonophosphate (cGMP)-dependent protein kinase II (cGKII)th at selectively blocks cGKII dependent phosphorylation of the vasodilator-stimulated phosphoprotein (VASP) in intestinal organoids. AP-C5 mitigates secretory response provoked by the GCC-activating Escherichia coli heat-stable toxin (STa) in mouse small intestinal tissue. | [storage]
Store at -20°C |
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