| Identification | Back Directory | [Name]
grandiflorenic acid | [CAS]
22338-67-6 | [Synonyms]
Kauradienoic acid
Grandiflorenicaci
grandiflorenic acid
Kaura-9(11),16-dien-18-oic acid
9,11-Dehydro-ent-kaurenoic acid
Kaura-9(11),16-diene-18-oic acid
(+)-Kaura-9(11),16-dien-18-oic acid
(+)-Kaura-9(11),16-diene-18-oic acid
Kaura-9(11),16-dien-18-oic acid, (4α)- | [Molecular Formula]
C20H28O2 | [MDL Number]
MFCD22417331 | [MOL File]
22338-67-6.mol | [Molecular Weight]
300.44 |
| Chemical Properties | Back Directory | [Melting point ]
155-157 °C | [Boiling point ]
447.5±44.0 °C(Predicted) | [density ]
1.12±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
4.69±0.40(Predicted) | [biological source]
plant | [Water Solubility ]
water: slightly soluble |
| Hazard Information | Back Directory | [Uses]
It is a natural product derived from plant source th at finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research. | [Biological Activity]
Grandiflorenic acid exhibits antibacterialanti-inflammatoryantileishmanial and wound-healing properties.
Grandiflorenic acid shows moderate cytotoxic (IC50 15μM in RAW264.7 cells) and antiplasmodial activities (IC50 23μM against P. falciparum).''Grandiflorenic acid (GFA) shows promise as an anticancer agent by inhibiting cell proliferation and reducing cell size in breast (MCF7)lung (A549)and liver (HuH7.5) tumor cell lines. Furtherit also shows effects on uterine motility throughout the estrus cycle suggesting it may have antifertility propertiespossibly by affecting hormones and adrenergic pathways in the uterus. | [target]
Estrogen receptor | Progestogen receptor |
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| Company Name: |
BioBioPha Co., Ltd.
|
| Tel: |
0871-65217109 13211707573; |
| Website: |
http://www.biobiopha.com |
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