| Identification | Back Directory | [Name]
(-)-Pyrenophorol | [CAS]
22248-41-5 | [Synonyms]
Pyrenophorol
(-)-Pyrenophorol
(3E,5S,8R,11E,13S,16R)-
(-)-5,13-Dihydroxy-8,16-dimethyl-1,9-dioxacyclohexadeca-3,11-diene-2,10-dione
(3E,5S,8R,11E,13S,16R)-5,13-Dihydroxy-8,16-dimethyl-1,9-dioxacyclohexadeca-3,11-diene-2,10-dione
1,9-Dioxacyclohexadeca-3,11-diene-2,10-dione, 5,13-dihydroxy-8,16-dimethyl-, (3E,5S,8R,11E,13S,16R)- | [Molecular Formula]
C16H24O6 | [MDL Number]
MFCD18379612 | [MOL File]
22248-41-5.mol | [Molecular Weight]
312.36 |
| Hazard Information | Back Directory | [Description]
Pyrenophorol is a fungal metabolite that has been found in Alternaria and has diverse biological activities. It inhibits human topoisomerase II α when used at concentrations of 75 and 100 μM. It is active against S. cerevisiae (MIC = 4 μM) and M. violaceum. Pyrenophorol induces leaf necrosis and chlorophyll retention in wild oats when used at a concentration of 64 μM. | [Uses]
Pyrenophorol is a simple macrocyclic dilactone produced by a number of species of pathogenic fungi, including Byssochlamys, Stenphyllum, Alternaria and Drechslera, first reported in the late 1960s. Pyrenophorol exhibits antibiotic, herbicidal and anthelmintic properties, and is a weak inhibitor of propyl endopeptidases. Pyrenophorol inhibits seed germination but once the seed is germinated, pyrenophlorol enhances root development but causes abnormal chlorophyll retention in leaf sections. | [Uses]
The macrolide dilactone Pyrenophorol was originally isolated from Byssochlamys niveah and Stemphylium radicinum. Pyrenophorol was moderately active against the fungus Microbotryum violaceum. It is an anti-fungal antibiotic produced by the plant pathogenic fungi Pyrenophora avenue and Stemphylium radicinum, which is closely related structurally to (-)-Pyrenophorol. | [Uses]
The macrolide dilactone Pyrenophorol
n anti-fungal antibiotic produced by the plant pathogenic fungi Pyrenophora avenue and Stemphylium radicinum, which is closely related structurally to (-)-
Pyrenophorol | [Definition]
ChEBI: Pyrenophorol is a macrolide. | [storage]
Store at -20°C |
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