| Identification | Back Directory | [Name]
LOXO-292 | [CAS]
2222755-14-6 | [Synonyms]
LOX0292
RET-IN-1
Pyrazolo[1,5-a]pyridine-3-carbonitrile, 4-[5-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]hept-3-yl]-2-pyrazinyl]-6-[(2R)-2-morpholinylmethoxy]- | [Molecular Formula]
C29H31N9O3 | [MDL Number]
MFCD32062760 | [MOL File]
2222755-14-6.mol | [Molecular Weight]
553.61 |
| Chemical Properties | Back Directory | [density ]
1.49±0.1 g/cm3(Predicted) | [storage temp. ]
Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). | [solubility ]
Soluble in DMSO | [form ]
solid | [pka]
8.23±0.40(Predicted) |
| Hazard Information | Back Directory | [Description]
RET-IN-1 is an oral and selective investigational drug in clinical development for the treatment of patients with cancers that harbor abnormalities in the rearranged during transfection (RET) kinase. | [Mechanism of action]
Receptor tyrosine kinase RET (rearranged during transfection) inhibitor |
|
| Company Name: |
Twochem Co.Ltd
|
| Tel: |
021-021-58111628 15800915896 |
| Website: |
www.twochem.com |
|