成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

ChemicalBook--->CAS DataBase List--->221244-14-0

221244-14-0

221244-14-0 Structure

221244-14-0 Structure
IdentificationBack Directory
[Name]

1 NM-PP1
[CAS]

221244-14-0
[Synonyms]

1 NM-PP1
Chebi:52309
PP1 ANALOG II
PP1 Analog II, 1NM-PP1
MUTANT KINASES INHIBITOR II
4-AMINO-1-TERT-BUYTL-3-(1-NAPHTHYLMETHYL)PYRAZOLO[3,4-D]PYRIMIDINE
4-AMINO-1-TERT-BUTYL-3-(1'-NAPHTHYLMETHYL)PYRAZOLO[3,4-D]PYRIMIDINE
1-tert-Butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-D]pyrimidin-4-amine
1-(1,1-Dimethylethyl)-3-(1-naphthalenylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
[Molecular Formula]

C20H21N5
[MDL Number]

MFCD03425470
[MOL File]

221244-14-0.mol
[Molecular Weight]

331.41
Chemical PropertiesBack Directory
[Appearance]

White Cyrstalline Solid
[Melting point ]

175-176°C
[Boiling point ]

545.7±45.0 °C(Predicted)
[density ]

1.25±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer
[solubility ]

Chloroform (Slightly), Methanol (Slightly, Heated)
[form ]

White solid
[pka]

4.50±0.30(Predicted)
[color ]

White to Beige
Hazard InformationBack Directory
[Chemical Properties]

White Cyrstalline Solid
[Uses]

A highly potent (IC50=4.3 nM) and uniquely specific tyrosine kinase inhibitor of a rationally engineered v-Src tyrosine kinase
[Description]

1-NM-PP1 is a cell permeable inhibitor of kinases that have been mutated, by a single base substitution, to become ‘a(chǎn)nalog sensitive’ (as), as compared to the wild-type kinase. 1-NM-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over v-Src (IC50 = 4.2 nM versus 28 μM, respectively). The homologous mutation in other kinases generated similar analog sensitivity (e.g., IC50 = 3.2 nM for c-Fyn-as1 versus 1.0 μM for c-Fyn; 5.0 nM for Cdk2-as1 versus 29 μM for Cdk2; 8.0 nM for CAMKII-as1 versus 24 μM for CAMKII). This approach has been used to elucidate functions of several kinases in both mammalian and yeast systems.
[Definition]

ChEBI: 1-NM-PP1 is a pyrazolopyrimidine. It has a role as a tyrosine kinase inhibitor.
[References]

[1] bishop ac1, ubersax ja, petsch dt, matheos dp, gray ns, blethrow j, shimizu e, tsien jz, schultz pg, rose md, wood jl, morgan do, shokat km. a chemical switch for inhibitor-sensitive alleles of any protein kinase. nature. 2000 sep 21; 407 (6802): 395-401.
Spectrum DetailBack Directory
[Spectrum Detail]

1 NM-PP1(221244-14-0)1HNMR
221244-14-0 suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Website: www.atkchemical.com
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695 , +8613203830695
Website: www.coreychem.com/
Company Name: Shenzhen Nexconn Pharmatechs Ltd
Tel: +86-755-89396905 +86-15013857715 , +86-15013857715
Website: http://m.is0513.com/ShowSupplierProductsList31188/0.htm
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: +8618523575427 , +8618523575427
Website: http://www.conier.com/
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000 , +1-00000000000
Website: https://www.targetmol.com/
Company Name: Chemia Biotechnology(Shanghai) Co., Ltd
Tel: +8613816753574 , +8613816753574
Website: www.chemia-pharm.com
Company Name: Finetech Industry Limited
Tel: +86-27-87465837 +8618971612321 , +8618971612321
Website: https://www.finetechnology-ind.com/
Company Name: Zhejiang J&C Biological Technology Co.,Limited
Tel: +1-2135480471 +1-2135480471 , +1-2135480471
Website: https://www.sarms4muscle.com
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105 , +1-13798911105
Website: https://www.invivochem.com/
Company Name: Coresyn Pharmatech Co., Ltd.
Tel: +86-571-86626709 +86-18157142896 , +86-18157142896
Website: http://www.coresyn.com/
Company Name: Nantong HI-FUTURE Biology Co., Ltd.
Tel: +undefined18051384581 , +undefined18051384581
Website: https://www.chemhifuture.com/
Company Name: ShenZhen Trendseen Biological Technology Co.,Ltd.
Tel: 13417589054 , 13417589054
Website: m.is0513.com/ShowSupplierProductsList1962465/0.htm
Company Name: Aceschem Inc.
Tel: +1-817863-6948 +1-(817)863-6948 , +1-(817)863-6948
Website: www.aceschem.com/
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525 , +8618327326525
Website: topule.com/
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Website: www.aladdinsci.com/
Company Name: Amadis Chemical Company Limited
Tel: 571-89925085
Website: http://www.amadischem.com
Company Name: Shanghai Boyle Chemical Co., Ltd.  
Tel:
Website: www.boylechem.com
Company Name: J & K SCIENTIFIC LTD.  
Tel: 010-82848833 400-666-7788
Website: http://www.jkchemical.com
Tags:221244-14-0 Related Product Information
194423-06-8 856925-71-8 1538604-68-0 49671-76-3 161973-10-0 206873-63-4 571190-30-2 219989-84-1 908115-27-5 908112-43-6 119433-80-6 142880-36-2 1204144-28-4 670220-88-9 25316-40-9 309739-67-1 221243-82-9