| Identification | Back Directory | [Name]
AC-IETD-PNA | [CAS]
219138-21-3 | [Synonyms]
AX-IETD-AMC
AC-IETD-AMC
AC-IETD-MCA
AC-IETD-PNA
Z-ALA-ALA-ASP-AFC
CASPASE-8 SUBSTRATE
GRANZYME B SUBSTRATE
CASPASE-8 SUBSTRATE I
AC-ILE-GLU-THR-ASP-PNA
AC-ILE-GLU-THR-ASP-AMC
AC-ILE-GLU-THR-ASP-MCA
CASPASE 8 FLUOROMETRIC SUBSTRATE
Caspase-8 Chromogenic Substrate I
AC-ILE-GLU-THR-ASP-P-NITROANILIDE
CASPASE 8 SUBSTRATE 1, CHROMOGENIC
GRANZYME B SUBSTRATE (CHROMOGENIC)
GRANZYME B SUBSTRATE (FLUOROGENIC)
AC-ILE-GLU-THR-ASP-PARANITROANILIDE
CASPASE 8 SUBSTRATE 1M, FLUOROGENIC
GRANZYME B SUBSTRATE 2 (CHROMOGENIC)
GRANZYME B SUBSTRATE I, COLORIMETRIC
GRANZYME B SUBSTRATE II (CHROMOGENIC)
N-ACETYL-ILE-GLU-THR-ASP P-NITROANILIDE
CASPASE-6/CASPASE-8 CHROMOGENIC SUBSTRATE
CASPASE-6/CASPASE-8 FLUOROGENIC SUBSTRATE
FLUOROGENIC CASPASE 8 SUBSTRATE AC-IETD-AMC
AC-ILE-GLU-THR-ASP-7-AMINO-4-METHYLCOUMARIN
N-ACETYL-ILE-GLU-THR-ASP-P-NITROANILIDE PNA
CASPASE-3 PROCESSING SUBSTRATE II (CHROMOGENIC)
N-ACETYL-ILE-GLU-THR-ASP-7-AMIDO-4-METHYLCOUMARIN
CASPASE-3 PROCESSING ENZYME SUBSTRATE (FLUOROGENIC)
N-ACETYL-ILE-GLU-THR-ASP-7-AMINO-4-METHYLCOUMARIN AMC
CASPASE-3 PROCESSING ENZYME SUBSTRATE II (CHROMOGENIC)
CASPASE-8 / CASPASE-3 PROCESSING ENZYME SUBSTRATE, FLUOROGENIC
CASPASE-8 / CASPASE-3 PROCESSING ENZYME SUBSTRATE (CHROMOGENIC)
CASPASE-3 PRECURSOR PROTEASE SUBSTRATES ;AC-ILE-GLU-THR-ASP-AMC
AC-IETD-PNA;AC-ILE-GLU-THR-ASP-PNA;CASPASE-8 CHROMOGENIC SUBSTRATE I
ACETYL-L-ISOLEUCYL-L-GLUTAMYL-L-THREONYL-L-ASPARTIC ACID ALPHA-(4-METHYLCOUMARYL-7-AMIDE) | [Molecular Formula]
C27H38N6O12 | [MDL Number]
MFCD01318840 | [MOL File]
219138-21-3.mol | [Molecular Weight]
638.62 |
| Chemical Properties | Back Directory | [Boiling point ]
1140.8±65.0 °C(Predicted) | [density ]
1.386±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
DMSO/DMF: 1 mg/mL
| [form ]
powder
| [pka]
4.03±0.10(Predicted) | [color ]
white
|
| Hazard Information | Back Directory | [Uses]
Fluorogenic substrate for caspase 8 and granzyme B. | [Biological Activity]
IETD is the sequence of amino acid residues 172-175 of procaspase 3which is cleaved during apoptosis to produce the p12 subunit and a p20 peptide th at is further cleaved to form the p17 subunit of mature caspase 3. |
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