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ChemicalBook--->CAS DataBase List--->21886-12-4

21886-12-4

21886-12-4 Structure

21886-12-4 Structure
IdentificationBack Directory
[Name]

N4-(6-AMINOPYRIMIDIN-4-YL)-SULFANILAMIDE HCL
[CAS]

21886-12-4
[Synonyms]

PNU 112455A
PNU 112455A HYDROCHLORIDE
XBXQRCJKDCEQBS-UHFFFAOYSA-N
N4-(6-AMINOPYRIMIDIN-4-YL)-SULFANILAMIDE HCL
4-[(6-amino-4-pyrimidinyl)amino]-benzenesulfonamide hydrochloride
[Molecular Formula]

C10H12ClN5O2S
[MDL Number]

MFCD00023272
[MOL File]

21886-12-4.mol
[Molecular Weight]

301.75
Chemical PropertiesBack Directory
[storage temp. ]

Inert atmosphere,2-8°C
[solubility ]

DMSO: soluble5mg/mL (clear solution)
[form ]

powder
[color ]

white to beige
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

PNU 112455A Hydrochloride is an ATP-competitive inhibitor of CDK2/cyclin E and CDK5/p25.
[IC 50]

CDK2: 3.6 μM (Km); CDK5: 3.2 μM (Km)
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