| Identification | Back Directory | [Name]
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester | [CAS]
21881-78-7 | [Synonyms]
Nimodipine EP Imp B
Nimodipine Impurity 2
Nilvadipine Impurity D
Nitrendipine Impurity 8
Nimodipine EP Impurity B
Nitrendipine Impurity1224
Nimodipine Impurity B Control
Bis(1-methylethyl) 2,6-Dimethyl-4-(
3-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine
diisopropyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
3,5-diisopropyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
(RS)-Di-iso-propyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
Bis(1-methylethyl) 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3,5-bis(1-methylethyl) ester | [Molecular Formula]
C21H26N2O6 | [MDL Number]
MFCD00347775 | [MOL File]
21881-78-7.mol | [Molecular Weight]
402.44 |
| Chemical Properties | Back Directory | [Melting point ]
123-125℃ (ethanol ) | [Boiling point ]
512.1±50.0 °C(Predicted) | [density ]
1.186±0.06 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
2.94±0.70(Predicted) | [color ]
Pale Beige |
| Hazard Information | Back Directory | [Uses]
3-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine (Nimodipine EP Impurity B) can be used in synthetic preparation of dihydropyridinedicarboxylic acid esters by methylimidazolium trifluoroacetate-catalyzed Hantzsch cyclocondensation reaction of oxo-carboxylic acid esters with aldehydes and ammonium acetate. It can also be used as an analyte for analytical study in developing and optimizing a validated isocratic reversed-phase high-performance liquid chromatograhy separation of nimodipine and impurities in tablets using experimental. design methodology. It is an impurity of the drug Nimodipine (N478200). |
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TOSUN PHARM
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