Chemical Properties | Back Directory | [Boiling point ]
665.5±55.0 °C(Predicted) | [density ]
1.251±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 300 mg/mL (756.72 mM) | [form ]
Solid | [pka]
13.93±0.46(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Description]
(S)-IDO1-IN-5 is the S-isomer of IDO1-IN-5. IDO1-IN-5 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[1]. | [storage]
Store at -20°C | [References]
[1]. Frank C. Dorsey, et al. Abstract 5245: Identification and characterization of the IDO1 inhibitor LY3381916. Cancer Research. 2018, 78(13). |
|
|